The New England Journal of Medicine has reported that an investigational vaccine protected some women against infection from one of the two types of herpes simplex viruses that cause genital herpes.
The vaccine was somewhat effective at preventing herpes simplex virus type 1 (HSV-1), but did not protect women from herpes simplex virus type 2 (HSV-2). There were less than half of the cases of genital herpes caused by HSV-1 and 58% fewer in those women who received the investigational vaccine compared to women who had received the control vaccine.
Both HSV-1 and HSV-2 are members of the herpes virus family. The HSV-2 causes lesions and blisters in the genital area. HSV-1 generally causes sores in the mouth and lips, although it increasingly has been found to cause genital disease as well.
There is currently is no cure or approved vaccine to prevent genital herpes infection, which affects about 25% of women in the United States and is one of the most common communicable diseases. Once inside the body the virus remains there permanently. The virus can cause severe neurological disease and even death in infants born to women who are infected with HSV and the virus is a risk factor for sexual transmission of HIV.
Patients with herpes simplex virus type 2 (HSV-2) taking high doses of antiviral therapy to control the disease continue to experience short episodes of subclinical shedding or reactivation, researchers reported online in Lancet.
The findings help explain why even high-doses of antiherpetic drugs do not prevent HSV transmission, according to Christine Johnston, MD, of the University of Washington in Seattle, and colleagues.
What are the symptoms of herpes?
1) Cold Sores
2) Blisters in the genital area that scab over and heal later
3) Burning, tingling or itchy sensation all over the skin
4) Swollen lymph nodes
5) Flu-like symptoms such as muscle aches and fever
6) Burning sensation or discharge from the genitals
7) Lower back pain
When an outbreak recurs, the most common symptom is usually the reappearance of blisters on the skin. However, these herpes symptoms are most severe during the first outbreak. The first year you will have more outbreaks and they will be less in subsequent years.
What will cause future outbreaks of herpes?
2) Too much stress and/or anxiety
3) Sexual intercourse
4) Fatigue and being run down
5) Another illness
How and when would you recommend a vaccine for Herpes?